Natural history collections — including preserved animals and plants, fossil material, geological evidence of change and even living collections — represent centuries of irreplaceable biodiversity documentation. As the world faces accelerating climate change, biodiversity loss, and diverse ecological pressures, these collections are emerging as critical research infrastructure that can inform decision making. Sharing the outcomes from research across our globally diverse cultures and knowledge systems can better inform the role natural history collections play. Adapting to climate fluctuations, social and political change and the ongoing challenge of protecting our collections under a range of financial and physical disruptions at a time, their value and uses are increasing. Please share your research and practice-based insights on how collections can be mobilised, interpreted, and expanded to meet present and future challenges.